In 1997, Alley received a further Emmy nomination for her work in the crime drama series The Last Don. In 2005, she played a fictionalized version of herself on Showtime's Fat Actress. She later appeared on the reality show Kirstie Alley's Big Life (2010), and was a contestant on the twelfth season of Dancing with the Stars (2011–12), finishing in second place. In 2013, she returned to acting with the title role on the sitcom Kirstie, and in 2016 joined the second season of the Fox comedy horror series Scream Queens. In 2018, Alley finished as runner-up on season 22 of the British reality series Celebrity Big Brother.
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